In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...
Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how risks are assessed, and how potential treatments move from early discovery ...
New grants support organoids, organs-on-chips, and in silico approaches to reduce reliance on animal models, but experts say ...
For decades, the pharmaceutical industry has discussed moving away from in vivo models in preclinical research. Now, it’s more than a conversation. The FDA’s roadmap for reducing animal testing, ...
The recent creation of the NIH Office of Research Integrity, Validation, and Adoption of New Approach Methodologies (ORIVA) is more than just an administrative shift. It represents a historic ...
In this Point of View column,, CEO of Taconic Biosciences, explores redefining preclinical models for the future of drug development.
Suggested Citation: "5 In Vitro Alternatives to Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in Support of ...
A social media post from the US Food and Drug Administration this week shows a big-eyed macaque staring out from behind bars. “Some drugs use 144 monkeys on average for preclinical testing,” the post ...