Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but ...

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites seeding new resistant tumors elsewhere in the body. Combating the problem has ...

Purinergic signaling, mediated by extracellular nucleotides such as ATP and UTP, has been increasingly studied for its role in regulating cellular communication. A new review by researchers in ...

A previous trial involving patients with metastatic prostate cancer that was resistant to androgen pathway modulation (formerly referred to as castration-resistant) showed that adding talazoparib ...

By their nature, cancer cells have different nutritional needs than healthy cells. "Cancer cells have a distinct metabolism," said Gary Patti, the Michael and Tana Powell Professor of Chemistry at ...

RASolute 302 findings herald a new standard of care in previously treated patients ...

Stopping cancer from coming back is the goal of new research from MUSC Hollings Cancer Center, where scientists are targeting cells that fuel the return of an aggressive pediatric brain tumor.