The way a key cellular motor works at an atomic level has been uncovered by simulations conducted by RIKEN biophysicists. This finding, published in the journal Proceedings of the National Academy of ...

Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like ...

Kinesin is a molecular motor that works as a cellular ‘porter’. Its job is to walk along microtubules, carrying membrane-bound bags of chemicals. To do this it must convert the chemical energy of ATP ...

A molecular model showing the rotor ring component of ATP synthase. In a molecular dynamics study, RIKEN researchers have discovered the ...

An octopus-shaped nanomachine hijacks tumor ATP leakage to power a self-amplifying cycle of membrane damage, drug delivery, and metabolic collapse in cancer cells.

Understanding this motion may help to tackle health problems that affect cilia, which range from fertility issues to lung disease and COVID-19. Using cryo-electron tomography, researchers have ...

Cancer cells undergo physically constraining processes, such as intravasation, extravasation, and tissue infiltration, that lead to acute mechanical stress. How mechanical confinement rewires the ...

It has been over a century since altered tumor cell metabolism was first observed. Since that time, metabolic reprogramming has become widely recognized as a core characteristic of cancer, and there ...

For more than 20 years, Makoto Miyata from Osaka City University has been studying the gliding motility of the parasitic bacterium Mycoplasma mobile (M. mobile). It is a mechanism consisting of an ...