AlphaFold is making great progress in protein structure prediction, not only for single-chain proteins but also for multi-chain protein complexes. When using AlphaFold-Multimer to predict ...

No "sticky ends"? No problem. A new study by NYU chemists finds that DNA tiles can assemble into 3D structures without the sticky cohesion of hydrogen bonding. This finding, published in Nature ...

Accurately capturing domain-domain interactions is key to understanding protein function and designing structure-based drugs. Although AlphaFold2 has made a breakthrough on single domain, it should be ...

We tend to view ourselves and the complex cells that build us as a distinct branch of the tree of life from the compact, ...

A new technique incorporates many different building blocks of cellular metamaterials into one unified graph-based representation. This can be used to make a user-friendly interface that can quickly ...