Scale-up involves increasing pump sizes, reactor volumes, and flow rates—but the process control logic and system ...

In the annals of napkin illustration, continuous drug tablet manufacturing may have only one entry: Fernando Muzzio’s 2003 depiction of a tableting line for Janet Woodcock, then head of the US Food ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

Moving away from fed-batch has significant sustainability and cost-saving benefits, according to industry working groups.

The collaboration with Pfizer aims to develop next-generation, continuous manufacturing for solid-dosage pharmaceuticals. GEA Process Engineering and G-CON Manufacturing have entered into a ...

The biopharmaceutical industry has seen substantial growth in recent years, generating novel biotherapeutics and biosimilars at an unprecedented rate. One of the biggest challenges in the industry is ...

A photo of technicians working in front of a process train. Novartis's continuous manufacturing center in Basel, Switzerland, replicates an end-to-end manufacturing process developed at the ...

Continuous casting remains a critical process in modern steel production, whereby molten steel is poured into a mould and solidified into semi-finished forms such as blooms, billets or slabs. This ...

Interest in intensified manufacturing is driving innovation in downstream technologies, according to the team behind a new predictive freeze-drying model designed with continuous processes in mind.