In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

An international team of scientists headed by researchers at the University of Edinburgh, has created a complete map showing how hundreds of possible mutations in a key cancer gene, CTNNB1, influence ...

What happens to the thousands of intestinal cells that have tumour-initiating DNA mutations? A study in mouse models shows that most are eliminated by strong negative selection, but those that survive ...

Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced ...

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...