The strong non-neutrality of most synonymous mutations—if found to be true for other genes and in other organisms—would have major implications for the study of human disease mechanisms, population ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

Occasionally, single-letter misspellings in the genetic code, known as point mutations, occur. Point mutations that alter the resulting protein sequences are called nonsynonymous mutations, while ...

For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...