The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

Bayesian inference provides a robust framework for combining prior knowledge with new evidence to update beliefs about uncertain quantities. In the context of statistical inverse problems, this ...

(A) Illustration of a distally mounted robotic endoscopic module integrated with the deployable ElastoSight probe for proprioceptive shape observation and force sensing. Schematics of the sliding ...