Error-corrected sequencing of non–B-cell fractions in CLL12/CLL14 detected CH in ~58% of CLL, with 35% meeting CHIP criteria. Cytotoxic regimens, especially chlorambucil-based therapy, were linked to ...

A hormone traditionally used to treat bone loss may hold the key to stopping chronic back pain at its source, according to a new study. Chronic back pain is often linked to the deterioration of spinal ...

Inflammation is how the body tells us something’s not right. Usually, that’s a good thing. You get hurt, and inflammatory cells come to the rescue. “It’s a protective mechanism of the body when we ...

Many people think of leukemia as a childhood cancer—and while it is the most common type in children under 15, it actually occurs most often in adults older than 55, per the National Cancer Institute.

Imagine a tiny superhero inside every cell of your body whose job is to stop damaged cells before they turn dangerous. That superhero is a gene called TP53, and for decades scientists have known it as ...

Tyrosine kinase inhibitors (TKIs) have transformed the treatment of chronic myeloid leukemia (CML). In a study involving patients with CML in high-income countries, approximately half the patients who ...

Leukemia exemplifies the transformation of modern medicine. Once almost always fatal and poorly understood, it can now in many cases be precisely classified and treated. The path to that point was ...

According to the review, modern treatments are not only improving survival but also reducing the need for aggressive chemotherapy and stem cell transplants.