Explore how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale.

In an ambitious collaboration, researchers added 1.8 million high-confidence protein complex structure predictions to the AlphaFold Database, accelerating molecular biology research.

Abstract: Multiple Sequence Alignment (MSA) is a fundamental challenge in bioinformatics, forming the basis for addressing numerous computational biology problems, e.g., protein structure prediction ...

Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.

The one thing Rams safety Quentin Lake wanted to improve this season above all else was ball production. It's safe to say he's done that, leading the league with five pass breakups through three games ...

i-Motifs (iMs) are cytosine-rich, four-stranded DNA structures with emerging roles in gene regulation and genome stability. Despite their biological relevance, genome-wide prediction of iM-forming ...

The EMBL File Format Converter is a specialized tool that converts biological sequence data from the EMBL format to various standard formats. It streamlines bioinformatics workflows by accurately ...

A command-line tool for detecting and extracting single homeologous polymorphisms (SHPs) from the subgenomes of allopolyploid species. This tool integrates three main algorithms, WGA, VCF2ALIGNMENT ...

Our STOCKHOLM File Format Converter is a specialized bioinformatics utility designed to improve interoperability among multiple sequence alignments (MSAs). This tool expertly converts alignments from ...

ABSTRACT: In malaria-endemic areas, the relatively high probability of hemoglobinopathies, especially sickle cell disease, raises important questions regarding the evolutionary interactions between ...